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Drug Topics: What patient populations are most likely to benefit from glucagon-like peptide-1 (GLP-1) receptor agonists for obesity management, and what criteria should be considered when recommending these medications

The National Academies Press, Washington, DC

The magnitude and rate of fat reduction with retatrutide is contingent on dosage, length of treatment, and patient-specific variables, emphasizing the requirement for individualized approaches

Patients with a pre-existing seizure disorder or epilepsy should inform their healthcare provider before starting any weight loss medication, as metabolic changes associated with treatment could theoretically affect seizure threshold or interact with antiepileptic medications

doi: 10.3390/biomedicines10102586 21 Di ChiaraTArganoCCorraoSScaglioneRLicataG